Skin & Dermatology ยท Topical
Luminance Brightening Cream
A brightening formula combining azelaic acid, hydroquinone, kojic acid and hydrocortisone, for melasma, sun spots and uneven skin tone.
This is a compounded preparation made by a licensed pharmacy. It is not FDA-approved, and it is prescribed only when a licensed provider determines it is appropriate for you.
Already know this is what you want? The second option books the appointment straight away. Not sure yet? See the labs first.
Your consult is free. We will not prescribe this, or anything, before a clinician has spoken with you. Final cost depends on the form and dose prescribed.
Mechanism
Four actives targeting pigment.
Hydroquinone and kojic acid both inhibit tyrosinase, the enzyme that drives melanin production, which is why they are paired here, each targets the same pathway from a slightly different angle.
Azelaic acid adds a second, gentler depigmenting and anti-inflammatory pathway, useful for the redness that can accompany melasma, and low-dose hydrocortisone is included to reduce irritation from the other actives.
Hydroquinone is one of the most effective treatments for stubborn pigmentation, but it is intended for limited courses under clinician supervision, prolonged unsupervised use carries a risk of a separate pigment condition called ochronosis, which is why this is prescription-only and monitored.
Safety and eligibility
Your consult and labs screen for all of the following.
- Pregnancy warning, Not for use during pregnancy, or if you are trying to become pregnant.
- Limited-course use, hydroquinone is typically prescribed for defined courses rather than indefinite daily use, follow your clinician's plan.
- Sun sensitivity, daily sunscreen is essential, pigment can worsen quickly with sun exposure during treatment.
- Initial irritation, mild stinging, dryness or redness is common when starting.
FAQ
Luminance Brightening Cream questions.
Hydroquinone-containing formulas are typically prescribed in limited courses; your clinician will set and review your plan.
It can help, but hydroquinone and tretinoin-class actives are not used during pregnancy, your clinician will advise on timing.
Yes, daily, pigment can return or worsen quickly without consistent sun protection.
Most patients see initial improvement at six to twelve weeks of consistent use.
We will not prescribe before we understand you.
Book a one-to-one consult with the clinical team. We talk through your goals, order the bloodwork that matters, and build a plan from what we find.