Skin & Dermatology ยท Topical
Stella+ Anti-Aging Cream
A nighttime cream combining GHK-Cu peptide, estriol, tretinoin and niacinamide, formulated to support fine lines, texture and tone, particularly in perimenopausal and postmenopausal skin.
This is a compounded preparation made by a licensed pharmacy. It is not FDA-approved, and it is prescribed only when a licensed provider determines it is appropriate for you.
Already know this is what you want? The second option books the appointment straight away. Not sure yet? See the labs first.
Your consult is free. We will not prescribe this, or anything, before a clinician has spoken with you. Final cost depends on the form and dose prescribed.
Mechanism
Built for hormonally aging skin.
Tretinoin drives collagen production and cell turnover, the best-studied effect of any topical anti-aging ingredient, and GHK-Cu peptide supports the body's own repair signaling.
Low-dose topical estriol, a weaker form of estrogen, has been studied for improving skin thickness, elasticity and hydration, particularly in perimenopausal and postmenopausal women, whose skin loses collagen more quickly as estrogen declines. Niacinamide supports barrier function and tone, helping the other actives work with less irritation.
This formula is positioned specifically for the hormonally-driven skin changes of perimenopause and menopause, rather than general anti-aging.
Safety and eligibility
Your consult and labs screen for all of the following.
- Pregnancy warning, Not for use during pregnancy, or if you are trying to become pregnant.
- Hormone-sensitive conditions, tell your clinician about any history of hormone-sensitive conditions before starting a topical estriol formula.
- Initial irritation, dryness, peeling or redness is common in the first few weeks as skin adjusts to tretinoin.
- Sun sensitivity, use daily sunscreen, treated skin is more sensitive to sun exposure.
FAQ
Stella+ Anti-Aging Cream questions.
Topical estriol is included specifically to address the thinning and loss of elasticity that comes with declining estrogen in perimenopause and menopause.
Tell your clinician your full history, they will determine whether topical estriol is appropriate for you.
Stella+ adds estriol specifically for hormonally-aging skin; Cashmere is built around caffeine and peptide for general firmness.
Most patients assess results at three to six months of consistent nightly use.
We will not prescribe before we understand you.
Book a one-to-one consult with the clinical team. We talk through your goals, order the bloodwork that matters, and build a plan from what we find.